| It has expanded spectrum, improved pharmacokinetics and better tolerability and drug interaction profiles. It has good activity against mycobacterium avium complex. It has acid stability and rapid oral absorption. It is largely excreted unchanged in bile. It has no interaction with cytochrome P450.
| Composition : | 100mg, 200 mg | | Indications : | Pharyngitis, tonsillitis, sinusitis, otitis media, pneumonias, acute exacerbations of chronic bronchitis, staphylococcal and streptococcal skin and soft tissue infections, chlamydial pulmonary and genital infections and gonorrhoea. Prophylaxis and treatment of MAC infection in AIDS patients. Other uses like typhoid, toxoplasmosis and malaria are being explored. | | Safety Profile : | It is comparatively newer antibiotics, should be used carefully with non-sedative antihistaminics. | | Adverse Effects : | Mild gastric upset, abdominal pain, headache, dizziness etc. | | Drug Interactions : | No interaction with hepatic cytochrome P450 enzyme | | Dosage : | 500mg OD orally, URTI/LRTI, skin & soft tissue infections: 500mg OD followed by 250mg OD
Children :10mg/kg/day for 3 days | | Purity : | Not less than 99%. | |
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