| Composition : | 250mg,500mg,750mg,1 gm |
| CEFUROXIME: :- | It is resistant to most beta lactamases and is active against a wide range of Gram-positive and Gram-negative organisms. The most important use of cefuroxime is in meningitis caused by H Influezae, Meningo Cocci and Pneumo Cocci because it attains high concentrations in CSF. |
| Indication : | Respiratory tract, Genito-urinary tract, skin and soft tissue infections, gonorrhoea, acute gonococal urethritis and cervicitis meningitis, prophylaxis against infections in surgical procedures. |
| Dosage :- | 750 mg thrice daily i.m. or i.v.Severe infections : 1.5 gm thrice daily i.v. Total dose 3-6 gm daily |
| Infants and Children :- | 30-100 mg/kg body wt daily in 3-4 divided doses |
| Neonates :- | 30-100 mg/kg body wt in 2-3 divided doses. |
| Meningitis : | 200-240 mg/kg body wt i.v. daily in 3-4 divided doses. |
| Contra-Indications :- | Patients with known hypersensitivity to cephalosporin antibiotics |
| Special Precautions :- | Anaphylactic reaction to Pencilins, Pseudo Membranous Colitis |
| Paediatrics :- | Not safe in children below 3 months |
| Pregnancy :- | Use with caution |
| Lactation :- | Use with caution |
| Side–effects :- | Skin rashes, Eosinophillia and transient increase of Hepatic Enzymes |
| Drug Interactions :- | Synergy with aminoglycosides |
| Purity : | Not less than 99%. |
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