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Home - Products - Oncology(Anti-Cancer-Injectables) - Cytosine Arabinoside Injection

Cytosine Arabinoside Injection

It is phosphorylated in the body to corresponding nucleotide, which inhibits DNA repair. Cytorabine is cell cycle specific and acts primarly during S phase. Its main use is to induce remission in acute leukemia.
Composition :100mg/1ml, 500mg/5ml, 1000mg/10ml
Indications :Acute leukemias, lymphosarcomas.
Dosage:3-6 mg/Kg body wt. i.v daily in 2 divided doses for 5-10 days.
Conraindications:Hypersensitivity, Pregnancy.
Special Precautions :Hepatic impairment.
Paediatrics : Indicated in certain leukemia, under strict supervision.
Pregnancy : Safety not established
Lactation : Safety not established
Elderly : Use with caution
Side- Effect :Bone marrow suppression. G.I.T disturbances.
Drug Interaction :Potentiates bone marrow depression with radiotheraphy and other myelotoxic drugs. Reduces plasma concentration of digoxin,antagonizes gentamycin. Decreased efficacy of flurocytosine.
Purity :Not less than 99%.
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