| Category: Anticancer
Each vial contains:-
Etoposide….. 100mg
Quality Specification:
Chromatographic Purity: NLT 99.5%
Pack Size:- 5ml
It is a recently developed semisynthetic derivative of podophyllotoxin, a plant glycoside. It is not a mitotic inhibitor, but arrests cells in the G2 phase. It has been primarily used in testicular tumours, lung cancer, hodgkin’s & other lymphomas.
| Composition : | 20mg/ml, 100mg/5ml |
| Indication : | Small cell lung cancer. Malignant lymphomas. Acute leukaemias, Testicular tumours . Bladder cancer & trophoblastic diseases. | | Dosage :- | Dose in combination with other chemotherapeutic agents: 50-100 mg/sqm body surface area/aily on days 1thorugh 5 to 100 mg/sqm/ BSA/daily on days 1,3,5. Give a gap of 3-4 wks to recover from toxicity before repeating. | | Contra Indications :- | Hypersensitivity, severe liver dysfunction. | | Special Precautions :- | Renal disease, infections, avoid contact with the skin, mucosa and eye. | | Paediatrics : | Safety not established. | | Pregnancy :- | Should not be used.. | | Lactation :- | Should not be used. | | Elderly :- | Should not be used. | | Side Effects :- | Alopecia, G.I.T. disturbances, nausea, vomiting, diarrhea, thrombophlebitis, neuritis, myelosuppression. | | Drug Interactions :- | Synergism with other cytotoxic drugs. | | Purity : | Not less than 99%. |
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