Fludarabine is a cytotoxic chemotherapeutic agent.
| Composition : | 50mg |
| Indications : | Treatment of patients with B- cell chronic lymphocytic leukemia (CLL) with sufficient bone marrow reserve and who have not responded to or whose disease has progressed during or after treatment with at least one alkylating agent containing regimen. |
| Contraindications : | Hypersensitivity to this drug or its components. Renal impaired patients (creatinine clearance <30 ml/ minute and patients with decompensated haemolytic anaemia. children. |
| Safety Profile : | When use at high doses fludarabine is associated with blindness, coma and death Pre existing skin cancer. |
| Dosage : | Adults: 25mg/m² body surface given daily for 5 consecutive days in every 28 days by IV route. |
| Purity : | Not less than 99%. |
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