Ofloxacin : It is a first generation fluoroquinolones. It has excellent gram negative activity and moderate to good activityagainst gram positive bacteria. It has good activity against chlamydia and mycoplasma. It also inhibits M. Tuberculosis and M. Leprae. It is relatively lipid soluble. Oral bioavailablity is high. Dexamethasone : Very potent and highly selective glucocorticoid. Long acting. Causes marked, pituitary-adrenal suppression, but fluid retention and hypertension are not a problem. It meets any emergency with intensified potency and strikingly rapid corticosteroid action, thus ensuring speedy reversal of the situation in the patients favour.