| It is a potent, highly selective antagonist at the 5HT 3 receptor site. It can effectively control vomiting due to anti cancer drugs as well as radio therapy and chemotherapy. It does not produce extrapyramidal symptoms.
| Composition : | 4mg/2ml, 8mg/4ml | | Indications : | Vomiting and nausea associated with anti cancer drugs, cytotoxic radio therapy, chemotherapy. Prophylaxis and prevention of post operative nausea and vomiting. | | Contraindications : | Hypersensitivity | | Safety Profile : | Liver diseases, constipation, headache. | | Adverse Effects : | Flushing, constipation, headache, rise in liver enzyme activity and rarely allergic reactions. | | Drug Interactions : | Dexamethasone increases the effect of drug. | | Dosage : | 8mg. as a slow IV. inj. given just before chemotherapy or radiotherapy or 8mg. orally 12 hrs. before this is followed by 8mg. orally every 12 hrs. | | Purity : | Not less than 99%. | |
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