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Home - Oncology (Anti Cancer Injectables) - Paclitaxel Injection

Paclitaxel Injection

Category: Anticancer
Each vial contains:-
Paclitaxel….. 6mg per ml
Quality Specification:
Chromatographic Purity: NLT 99.5%
Pack Size:- 5ml ,17ml , 43.4 ml

It is a diterpenoid compound with anti-tumour activity. It binds specifically to the tubulin subunit of microtubule and appears to antagonise the disassembly of this cytoskeletal protein.
Composition : 2.5mg/2.5ml,4mg/4ml
Indication : Metastatic ovarian and breast cancer.
Dosage :- 175 mg per square metre by iv infusion over 3 hrs. repeat every 3 weeks. Pretreat with corticosteroids, antihistaminics and H2 antagonists.
Contra Indications :-Hypersensitivity.
Special Precautions :- Monitor heamatological functions.
Paediatrics : Not recommended.
Pregnancy :- Not usually prescribec.
Lactation :- Not advised.
Side Effects :- Bone marrow depression, hypersensitivity reactions, myalgia, chest pain, bradycardia, a stocking –glove sensory neuropathy, mucositis, nausea, vomiting, diarrhea, alopecia.
Purity :Not less than 99%.
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Paclitaxel-Injection
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