| It is obtained from culture of human kidney cells. It is not antigenic in nature.
| Composition : | 250000IU, 500000IU, 75OOOOOIU | | Indications : | Acute myocardial infarction, acute thrombosis of arteries, pulmonary embolism and deep vein thrombosis. | | Contraindications : | Any surgical procedure with in last 10 days, recent trauma, peptic ulcer, pregnancy, severe uncontrolled hypertension, bleeding disorders. | | Safety Profile : | Lactation, cerebrovascular diseases, atrial fibrillation. | | Adverse Effects : | Haemorrhage, vomiting. | | Drug Interactions : | Aspirin, dipyridamole, heparin and oral anticoagulants increase the risk of haemorrhage. | | Dosage : | Acute myocardial infarction 10000 I.U./kg intravenously or 2000000 I.U. as bolus intravenous infusion over 1 hour or 10000 I.U per min. by intracoronary route. Clot is usually lysed within 30 mts. of intravenous route administration or 1 hour of intracoronary admn. | | Purity : | Not less than 99%. | |
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