| It has potent antiarrhythmic activity more so in supraventricular arrhythmias because of its potent calcium channel blocking property. Same activity is responsible for its antianginal and antiischemic action.
| Composition : | 5mg/ 2ml | | Indications : | PSVT, atrial flutter/fibrillation with tachyarrhythmias and pre mature beats. Angina pectoris, chronic coronary insufficiency, variant angina, hypertension. | | Contraindications : | Acute M.I., cardiovascular shock, severe AV block and sick sinus syndrome. | | Safety Profile : | Ability to do skilled job may be impaired, hepatic & renal impairment. | | Adverse Effects : | Constipation, nausea, vertigo, dizziness, headache, flushing, faigue, ankle oedema, erythromelalia and paraesthesia. | | Drug Interactions : | Antihypertensives including beta blockers, neuromuscular blockers, digitalis and carbamazepine actions repotentiated. Use with quinidine may cause cardiac depression. | | Dosage : | Adults - 40-80 mg 2-3 times daily orally. i.v. dose 5mg slowly, repeat further 5mg if needed, children - upto 6 yrs. 40-80mg twice a day, 6-12 yrs - 40-120mg twice a day. | | Purity : | Not less than 99%. |
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